Reacción #76932

ord-019d97f80953490ea464d9fde46e3bf7

Ecuación de reacción

COc1ccc(CC2NCCc3c(OC)ccc(OC)c32)cc1OC
1-(3,4-Dimethoxy-benzyl)-5,8-dimethoxy-1,2,3,4-tetrahydroisoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
COc1ccccc1CN
2-methoxybenzylamine
→
COc1ccccc1CNC(=O)CN1CCc2c(OC)ccc(OC)c2C1Cc1ccc(OC)c(OC)c1
2-[1-(3,4-Dimethoxy-benzyl)-5,8-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl]-N-(2-methoxy-benzyl)-acetamide

Reactantes

COc1ccc(CC2NCCc3c(OC)ccc(OC)c32)cc1OC
1-(3,4-Dimethoxy-benzyl)-5,8-dimethoxy-1,2,3,4-tetrahydroisoquinoline
O=C(Br)CBr
2-bromoacetyl bromide
COc1ccccc1CN
2-methoxybenzylamine

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

prepared by reaction of 1-(3,4-Dimethoxy-benzyl)-5,8-dimethoxy-1,2,3,4-tetrahydroisoquinoline and 2-bromoacetyl bromide with 2-methoxybenzylamine

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US06703392B2uspto-grants-2004_03