Reacción #7654

Ecuación de reacción

6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one

1-methylcyclohexanecarbonyl chloride

→

N-[1-(3-Cyclopentyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]-1-methylcyclohexanecarboxamide

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe crude product is used in the next step without further purification

Procedimiento

In analogy to the procedure for Example 36A, 150 mg (0.67 mmol) 6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one, 120 mg (0.74 mmol) 1-methylcyclohexanecarbonyl chloride and proportionate amounts of the other reagents are used. The crude product is used in the next step without further purification.

Fuente