Reacción #7640

Ecuación de reacción

6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one

cyclopentanecarbonyl chloride

→

N-[1-(3-Cyclopentyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]cyclobutanecarboxamide

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe crude product is used in the next step without further purification

Procedimiento

In analogy to the procedure for Example 36A, 200 mg (0.90 mmol) 6-(1-aminopropyl)-3-cyclopentyl-1,2,4-triazin-5(4H)-one, 120 mg (0.90 mmol) cyclopentanecarbonyl chloride and proportionate amounts of the other reagents are used. The crude product is used in the next step without further purification.

Fuente