Reacción #75760

Ecuación de reacción

benzoyl chloride

4-(4-amino-2-butyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)butaneamine

→

N-[4-(4-amino-2-butyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)butyl]benzamide

Rendimiento 55.0%

Condiciones de reacción

Procedimiento

Using the general method of Example 47, benzoyl chloride (56 μL, 0.48 mmol) was reacted with 4-(4-amino-2-butyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)butaneamine (0.15 g, 0.48 mmole) to provide 0.11 g of N-[4-(4-amino-2-butyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)butyl]benzamide as a white solid. Analysis: Calculated for C24H28N6O+¼H2O: %C, 68.47; %H, 6.82; %N, 19.96. Found: %C, 68.24; %H, 6.76; %N, 19.90.

Fuente