Reacción #75575

Ecuación de reacción

4-methoxybenzyl chloride

phthalimide potassium

→

N-(4-methoxybenzyl)phthalimide

Rendimiento 90.8%

Disolventes

dimethylformamide

Condiciones de reacción

Tratamiento posterior

1. 1
   TemperaturaAfter cooling
2. 2
   Otrothe resulting precipitates
3. 3
   Filtraciónwere collected by filtration
4. 4
   LavadoThese were washed with water
5. 5
   Otrodried

Procedimiento

A mixture of 20 g 4-methoxybenzyl chloride, 26 g phthalimide potassium, and 100 ml dimethylformamide was stirred at 50° C. for 5 hr. After cooling, the reaction solution was poured into ice water and the resulting precipitates were collected by filtration. These were washed with water and dried to give 31 g of N-(4-methoxybenzyl)phthalimide.

Fuente