Reacción #75421

ord-eaebb6f998044b49a7795000362689e0

Ecuación de reacción

NC(=O)CC[C@H](N)C(=O)O
L-glutamine
O=C(O)[C@@H]1CCCN1
L-proline
CC(=O)SCC(CSC(C)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)O
N-[2-(acetylthiomethyl)-3-(acetylthio)propanoyl]-L-glutamine
→
NC(=O)CC[C@H](NC(=O)C(CS)CS)C(=O)O
N-[2-(Mercaptomethyl)-3-mercaptopropanoyl]-L-glutamine

Reactantes

—
1-[2-(mercaptomethyl)-3-mercaptopropanoyl]-L-glutamine
NC(=O)CC[C@H](N)C(=O)O
L-glutamine
O=C(O)[C@@H]1CCCN1
L-proline
CC(=O)SCC(CSC(C)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)O
N-[2-(acetylthiomethyl)-3-(acetylthio)propanoyl]-L-glutamine

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    Otroare obtained

Procedimiento

By substituting L-glutamine for the L-proline in the procedure of Example 3B, and then submitting the product to the procedure of Example 4, N-[2-(acetylthiomethyl)-3-(acetylthio)propanoyl]-L-glutamine and 1-[2-(mercaptomethyl)-3-mercaptopropanoyl]-L-glutamine are obtained.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US04176235uspto-grants-1979_11