Reacción #74918

Ecuación de reacción

20-Deoxynarasin sodium

→

20-deoxynarasin

Rendimiento 71.8%

Disolventes

ethyl acetate

dioxane

Condiciones de reacción

Tratamiento posterior

1. 1
   LavadoThis solution was washed with 0.1 N HCl (10 ml)
2. 2
   OtroThe resulting organic layer was evaporated to dryness
3. 3
   Otroto give a residue which

Procedimiento

20-Deoxynarasin sodium salt (200 mg) was dissolved in ethyl acetate (10 ml). This solution was washed with 0.1 N HCl (10 ml) and then twice with water (5 ml). The resulting organic layer was evaporated to dryness to give a residue which was redissolved in dioxane and lyophilized to give 139.6 mg of 20-deoxynarasin free acid as a white solid.

Fuente