Reacción #737121

Ecuación de reacción

ethyl 2-(2-aminoanilino)-6-methoxybenzo[b]thiophene-3-carboxylate

1-methylpiperazine

anisole

→

3-methoxy-12-(4-methylpiperazin-1-yl)-6H-[1]benzothieno[2,3-b][1,5]benzodiazepine

Condiciones de reacción

Procedimiento

In the same manner as in Example 1 and using ethyl 2-(2-aminoanilino)-6-methoxybenzo[b]thiophene-3-carboxylate, 1-methylpiperazine, anisole and titanium tetrachloride, 3-methoxy-12-(4-methylpiperazin-1-yl)-6H-[1]benzothieno[2,3-b][1,5]benzodiazepine is obtained.

Fuente