Reacción #735619

Ecuación de reacción

1,12-dodecanediamine

cyclohexyl isocyanate

toluene

isocyanate

→

1,18-dicyclohexyl-1,3,16,18-tetraaza-2,17-octadecanedione

Disolventes

THF toluene

THF toluene

Condiciones de reacción

Tratamiento posterior

1. 1
   Otro3-neck flask equipped with a thermometer, magnetic stirrer, pressure
2. 2
   Otronitrogen purge
3. 3
   Temperaturaheating mantle
4. 4
   workup.ADDITIONslowly dropped into the stirred
5. 5
   TemperaturaThe temperature was raised to 80° C.
6. 6
   Temperaturathe reaction mixture was refluxed for 12 hours

Procedimiento

30.04 gm (0.240 mole) of cyclohexyl isocyanate was dissolved in 400 mL of 1:1 THF/toluene in a 1000 mL round bottom, 3-neck flask equipped with a thermometer, magnetic stirrer, pressure equalizing dropping funnel, nitrogen purge and heating mantle. The solution in the flask was heated to 40° C. 24.04 gm (0.240 mole) of 1,12-dodecanediamine was dissolved in 400 mL of 1:1 THF/toluene and slowly dropped into the stirred, heated solution of isocyanate. After addition of the diamine, an additional 100 mL of toluene was added to the flask. The temperature was raised to 80° C. and the reaction mixture was refluxed for 12 hours.

Fuente