Reacción #72533

Ecuación de reacción

trichloroacetyl chloride

pyrrole

potassium carbonate

→

title product

2,2,2-Trichloro-1-(1H-pyrrol-2-yl)ethanone

Disolventes

ethyl ether

water

ethyl ether

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe phases are separated
2. 2
   Secadothe organic phase is dried over sodium sulphate
3. 3
   Filtraciónfiltered
4. 4
   workup.ADDITIONActive carbon is added to this organic phase
5. 5
   workup.STIRRINGAfter stirring for 5 minutes
6. 6
   Filtraciónthe organic phase is filtered
7. 7
   Otroevaporated to dryness

Procedimiento

To a solution of trichloroacetyl chloride (160.7 mmoles) in ethyl ether (26 ml) there is added, dropwise over a period of 3 hours, a solution of pyrrole (149 mmoles) in ethyl ether (83 ml). After stirring for a further hour, a solution of potassium carbonate (94 mmoles) in water (39 ml) is added dropwise. The phases are separated and the organic phase is dried over sodium sulphate and filtered. Active carbon is added to this organic phase. After stirring for 5 minutes, the organic phase is filtered and evaporated to dryness to yield the title product.

Fuente