Reacción #722660

ord-3d73f6e20225411fb67d8301ad89e7e7

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    Otroobtained
  2. 2
    Otrohydrolysis in the same manner
  3. 3
    Otroto give the subject compound

Procedimiento

In working example 77, 2-acetamido-2-ethyl-4-(4-octanoylphenyl)butyl acetate obtained by using ethylmalonic acid diethyl ester instead of propylmalonic acid diethyl ester, is subjected to reduction in the same manner as working example 2 (7) and then hydrolysis in the same manner as working example 78 to give the subject compound.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US06187821B1uspto-grants-2001_02