Reacción #72070

Ecuación de reacción

ethyl cis(±)-2-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)-5-methylpyridine-4-carboxylate

Ethyl cis(±)-2-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)-5-methylpyridine-4-carboxylate

→

title compound

Rendimiento 18.5%

Ethyl cis(±)-2-(4-amino-3-methoxypiperidin-1-yl)-5-methylpyridine-4-carboxylate

Rendimiento 18.5%

Condiciones de reacción

Procedimiento

The same operation as in Example (160c) was performed using ethyl cis(±)-2-(4-{[(benzyloxy)carbonyl]amino}-3-methoxypiperidin-1-yl)-5-methylpyridine-4-carboxylate obtained in Example (180a) (207 mg, 0.48 mmol) and a 10% palladium-carbon catalyst (200 mg), to obtain 26.1 mg of the title compound as a yellow oily substance.

Fuente