Reacción #716727

Ecuación de reacción

2-(4-(adamantan-1-yl)phenoxy)acetic acid

1-(prop-2-yn-1-yl)piperazine

→

2-(4-(adamantan-2-yl)phenoxy)-1-(4-(prop-2-yn-1-yl)piperazin-1-yl)ethanone

Rendimiento 178.9%

title compound

2-(4-(Adamantan-1-yl)phenoxy)-1-(4-(prop-2-yn-1-yl)piperazin-1-yl)ethanone

Condiciones de reacción

Procedimiento

The title compound was prepared from 2-(4-(adamantan-1-yl)phenoxy)acetic acid (0.13 g, 0.45 mmol) and 1-(prop-2-yn-1-yl)piperazine (0.056 g, 0.45 mmol) according to the example 1, which was given 2-(4-(adamantan-2-yl)phenoxy)-1-(4-(prop-2-yn-1-yl)piperazin-1-yl)ethanone as a white solid (0.158 g, 89.3% yield).

Fuente