Reacción #71628

ord-2dc8ccd60ede4c1297b0d65fbfc72a74

Ecuación de reacción

O=C(OCc1ccccc1)N1CCNCC1
phenylmethyl 1-piperazinecarboxylate
O=Cc1ccc(Br)cc1
4-bromobenzaldehyde
C[C@H]1CN(Cc2ccc(Br)cc2)CCN1C(=O)OCc1ccccc1
D6
C[C@H]1CN(Cc2ccc(Br)cc2)CCN1C(=O)OCc1ccccc1
Phenylmethyl (2S)-4-[(4-bromophenyl)methyl]-2-methyl-1-piperazine Carboxylate
→
O=C(OCc1ccccc1)N1CCN(Cc2ccc(Br)cc2)CC1
title compound
O=C(OCc1ccccc1)N1CCN(Cc2ccc(Br)cc2)CC1
Phenylmethyl 4-[(4-bromophenyl)methyl]-1-piperazinecarboxylate

Reactantes

O=C(OCc1ccccc1)N1CCNCC1
phenylmethyl 1-piperazinecarboxylate
O=Cc1ccc(Br)cc1
4-bromobenzaldehyde
C[C@H]1CN(Cc2ccc(Br)cc2)CCN1C(=O)OCc1ccccc1
D6
C[C@H]1CN(Cc2ccc(Br)cc2)CCN1C(=O)OCc1ccccc1
Phenylmethyl (2S)-4-[(4-bromophenyl)methyl]-2-methyl-1-piperazine Carboxylate

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

The title compound was prepared from phenylmethyl 1-piperazinecarboxylate and 4-bromobenzaldehyde using a method to that described for D6

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US08536182B2uspto-grants-2013_09