Reacción #71190

ord-59d23d0397004ee587c35993f4467100

Ecuación de reacción

CC1(c2ccc(Cn3ncc(N)n3)s2)OCCO1
2-[5-(2-methyl-[1,3]dioxolan-2-yl)-thiophen-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine
O=C(O)c1ncoc1-c1ccccc1
5-phenyl-oxazole-4-carboxylic acid
→
CC(=O)c1ccc(Cn2ncc(NC(=O)c3ncoc3-c3ccccc3)n2)s1
5-Phenyl-oxazole-4-carboxylic acid [2-(5-acetyl-thiophen-2-ylmethyl)-2H-[1,2,3]triazol-4-yl]-amide

Reactantes

CC1(c2ccc(Cn3ncc(N)n3)s2)OCCO1
2-[5-(2-methyl-[1,3]dioxolan-2-yl)-thiophen-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine
O=C(O)c1ncoc1-c1ccccc1
5-phenyl-oxazole-4-carboxylic acid

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

Following general procedure A followed by B, starting from 2-[5-(2-methyl-[1,3]dioxolan-2-yl)-thiophen-2-ylmethyl]-2H-[1,2,3]triazol-4-ylamine and 5-phenyl-oxazole-4-carboxylic acid.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US08536209B2uspto-grants-2013_09