Reacción #711061

ord-733a2e2b2ae74c02a65042d2b3562924

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

By using 2-methyl-4-[5-[4-(trifluoromethyl)-1-(2-trimethylsilylethoxymethyl)-imidazol-2-yl]-2-pyridyl]phenol (224 mg) and tert-butyl 3-hydroxy-2,2-dimethylpropanoate (284 mg), the procedure was carried out in the same manner as in Example 1-1) to obtain tert-butyl 2,2-dimethyl-3-[2-methyl-4-[5-[4-(trifluoromethyl)-1-(2-trimethylsilylethoxymethyl)imidazol-2-yl]-2-pyridyl]phenoxy]propanoate (104 mg).

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US09302996B2uspto-grants-2016_04