Reacción #710460
ord-d84848f7159b4522a4d7d69ea5449e08
Ecuación de reacción
2-amino-3,5-dichlorobenzoic acid methyl ester
tert-butylamine
→
N-tert-butyl-2-amino-3,5-dichlorobenzamide
Rendimiento 90.4%
Reactivos
Ninguno
Disolventes
Condiciones de reacción
Temperatura
64°CELSIUS
Condiciones detalladas
See reaction.notes.procedure_details.
Tratamiento posterior
- 1workup.ADDITIONwere added
- 2Otroreacted for 5 hours
Procedimiento
To a 100 mL round-bottom flask, 0.1 mol of 2-amino-3,5-dichlorobenzoic acid methyl ester having a structure as shown in VIII-1, 100 mL of methanol, and 0.4 mol of tert-butylamine were added, heated to 64° C. and reacted for 5 hours, after treatment 23.5 grams of N-tert-butyl-2-amino-3,5-dichlorobenzamide having a structural formula of III-1 was obtained, and the yield was 90.4%;