Reacción #70835

Ecuación de reacción

6-chloronicotinic acid

SOCl2

→

desired product

Rendimiento 93.0%

6-Chloronicotinoyl chloride hydrochloride

Rendimiento 93.0%

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturato reflux for 2 h
2. 2
   OtroThe SOCl2 was evaporated to dryness

Procedimiento

A solution of 6-chloronicotinic acid (10.00 g, 63.5 mmol) in SOCl2 (37 mL) was heated to reflux for 2 h. The SOCl2 was evaporated to dryness, to afford 12.56 g of the desired product (yield: 93%).

Fuente