Reacción #69944

Ecuación de reacción

10-oxa-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione

methanol

methanol

→

1-methyl-10-oxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione

Condiciones de reacción

Tratamiento posterior

1. 1
   Otrois passed at a rate of 1.5 ml/min through a Thalis H-cube apparatus (from Thalis nanotec) set-up at 40° C.
2. 2
   OtroThe so obtained solution
3. 3
   Otrois evaporated

Procedimiento

The 10-oxa-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione (10.5 g) is dissolved in methanol (700 ml). The methanol solution is passed at a rate of 1.5 ml/min through a Thalis H-cube apparatus (from Thalis nanotec) set-up at 40° C. and 40 bar and fitted with a 10% Pd/C cartridge. The so obtained solution is evaporated to give 1-methyl-10-oxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione (9.2 g).

Fuente