Reacción #696695

Ecuación de reacción

1,4-diaminobutane

triethylamine

2-chloro-2-methyl-3-nitrosopentane

→

2-(4-aminobutyl)amino-2-methyl-3-pentanone oxime

Disolventes

acetonitrile

acetonitrile

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroto precipitate
2. 2
   workup.STIRRINGThe reaction mixture was stirred overnight
3. 3
   Filtraciónthe product was filtered off
4. 4
   Otrodried in vacuo
5. 5
   Otroto give a white powder, (0.5 g; 86%)

Procedimiento

To a stirred solution of 1,4-diaminobutane (0.26 g; 2.9 mmol) and triethylamine (0.33 g; 3.2 mmol) in acetonitrile (5 ml) was added a solution of 2-chloro-2-methyl-3-nitrosopentane (0.485 g; 3.24 mmol) in acetonitrile (5 ml). After stirring for ca 10 minutes the product began to precipitate. The reaction mixture was stirred overnight and the product was filtered off and dried in vacuo to give a white powder, (0.5 g; 86%).

Fuente