Reacción #6954

Ecuación de reacción

2-cyano-3-cyclohexyl-3-oxo-propionic acid ethyl ester

→

3-Cyclohexyl-3-oxo-propionitrile

Disolventes

DMSO water

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe reaction mixture was partitioned between ether and 1N HCl
2. 2
   Secadothe organic phase was dried with MgSO4
3. 3
   Otrothe solvent removed under reduced pressure

Procedimiento

A solution of 2-cyano-3-cyclohexyl-3-oxo-propionic acid ethyl ester in DMSO:water (10:1) was stirred at 120° C. for 2 hours. The reaction mixture was partitioned between ether and 1N HCl, the organic phase was dried with MgSO4 and the solvent removed under reduced pressure.

Fuente