Reacción #69024

Ecuación de reacción

bis(pinacolato)diboron

2,4-dichloropyrimidine

3-morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

3-bromo-5-morpholinobenzonitrile

→

3-(2-Chloropyrimidin-4-yl)-5-morpholinobenzonitrile

Condiciones de reacción

Tratamiento posterior

1. 1
   Otrowas synthesized

Procedimiento

3-(2-Chloropyrimidin-4-yl)-5-morpholinobenzonitrile was prepared according procedure B from 2,4-dichloropyrimidine and 3-morpholino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile which was synthesized by following procedure A using 3-bromo-5-morpholinobenzonitrile and bis(pinacolato)diboron.

Fuente