Reacción #688304

Ecuación de reacción

product

ethyl 2-(cyclohexylamino)nicotinate

product

ethyl 2-[(2-ethylbutyl)amino]nicotinate

→

title compound

1-cyclohexyl-2H-pyrido[2,3-d][1,3]oxazine-2,4(1H)-dione

Condiciones de reacción

Procedimiento

The title compound was prepared according to the procedure of Example 3B substituting the product of Example 81A for the product of Example 3A (0.171 g, 35%). 1H NMR (300 MHz, CDCl3) δ 1.37 (m, 4H), 1.73 (m, 2H), 1.91 (m, 2H), 2.47 (ddd, J=24.82, 12.32, 3.31 Hz, 2H), 5.28 (tt, J=12.27, 3.72 Hz, 1H), 7.24 (dd, J=6.99, 4.04 Hz, 1H), 8.41 (dd, J=7.72, 2.21 Hz, 1H), 8.70 (dd, J=4.78, 2.21 Hz, 1H).

Fuente