Reacción #684981

Ecuación de reacción

Trifluoroacetic acid

(4-(dodecanoylsulfamoyl)benzyl)carbamic acid tert-butyl ester

→

trifluoroacetic salt

Rendimiento 128.9%

4-Aminomethyl-N-(dodecanoyl)benzenesulfonamide

Rendimiento 128.9%

Disolventes

dichloromethane

Condiciones de reacción

Tratamiento posterior

1. 1
   Otrowas at room temperature
2. 2
   OtroThe solvents were removed in vacuo
3. 3
   workup.DISSOLUTIONThe residue was dissolved in dichloromethane (40 ml)
4. 4
   Otrothe solvent was removed in vacuo

Procedimiento

Trifluoroacetic acid (25 ml) was at room temperature added to a solution of (4-(dodecanoylsulfamoyl)benzyl)carbamic acid tert-butyl ester (170 mg, 0.40 mmol) in dichloromethane (25 ml). The reaction mixture was stirred for 1 h at room temperature. The solvents were removed in vacuo. The residue was dissolved in dichloromethane (40 ml) and the solvent was removed in vacuo. The latter procedure was repeated once to give 0.19 g of the trifluoroacetic salt of 4-aminomethyl-N-(dodecanoyl)benzenesulfonamide.

Fuente