Reacción #684948

Ecuación de reacción

Thionyl chloride

4-n-butylbenzyl alcohol

→

title compound

Rendimiento 104.9%

1-(Chloromethyl)-4-n-butylbenzene

Rendimiento 104.9%

Disolventes

ether

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroAfter concentration of the mixture, excess thionyl chloride was removed by azeotropic distillation with benzene

Procedimiento

Thionyl chloride (2.5 ml, 34 mmol) was added to a solution of 4-n-butylbenzyl alcohol (2.0 g, 12 mmol) in ether (25 ml), and this mixture was stirred at room temperature for 3 hours. After concentration of the mixture, excess thionyl chloride was removed by azeotropic distillation with benzene to give the title compound (2.3 g). This compound was used in the following reaction without purification.

Fuente