Reacción #684939

Ecuación de reacción

4-methoxy-4′-(di-p-tolylamino)stilbene

sodium ethanethiolate

water

hydrochloric acid

→

4-hydroxy-4′-(di-p-tolylamino)stilbene

Disolventes

N,N-dimethylformamide

Condiciones de reacción

Tratamiento posterior

1. 1
   Otroreacted for 5 hours at 130° C
2. 2
   TemperaturaThe mixture is cooled down
3. 3
   ExtracciónThe objective material is extracted
4. 4
   LavadoThe extracted liquid is washed with water
5. 5
   Otrodried
6. 6
   OtroThe crude objective material is prepared
7. 7
   Otroby removing the solvent (i.e., N,N-dimethylformamide)
8. 8
   OtroFurther, the crude objective material is purified with a column chromatography

Procedimiento

The above-prepared 4-methoxy-4′-(di-p-tolylamino)stilbene and twice equimolar amount of sodium ethanethiolate are dissolved in N,N-dimethylformamide, and reacted for 5 hours at 130° C. The mixture is cooled down, and then poured into water and neutralized with hydrochloric acid. The objective material is extracted therefrom using acetic acid. The extracted liquid is washed with water, and then dried. The crude objective material is prepared by removing the solvent (i.e., N,N-dimethylformamide) therefrom. Further, the crude objective material is purified with a column chromatography using silica gel. Thus, 4-hydroxy-4′-(di-p-tolylamino)stilbene (i.e., objective material) is prepared.

Fuente