Reacción #68422

ord-c5926f83dae44f278189c0d69924e5eb

Ecuación de reacción

CCOC(=O)c1c(C(C)C)[nH]c2cc([N+](=O)[O-])c(F)cc12
ethyl5-fluoro-2-isopropyl-6-nitro-1H-indole-3-carboxylate
CCOC(=O)c1c(C(C)C)[nH]c2cc([N+](=O)[O-])c(F)cc12
Compound 168
CCOC(=O)c1c(C(C)C)[nH]c2cc([N+](=O)[O-])c(F)cc12
ethyl5-fluoro-2-isopropyl-6-nitro-1H-indole-3-carboxylate
BrCc1ccccc1
benzyl bromide
→
CCOC(=O)c1c(C(C)C)n(Cc2ccccc2)c2cc([N+](=O)[O-])c(F)cc12
title compound
CCOC(=O)c1c(C(C)C)n(Cc2ccccc2)c2cc([N+](=O)[O-])c(F)cc12
Ethyl 1-Benzyl-5-fluoro-2-isopropyl-6-nitro-1H-indole-3-carboxylate

Reactantes

CCOC(=O)c1c(C(C)C)[nH]c2cc([N+](=O)[O-])c(F)cc12
ethyl5-fluoro-2-isopropyl-6-nitro-1H-indole-3-carboxylate
CCOC(=O)c1c(C(C)C)[nH]c2cc([N+](=O)[O-])c(F)cc12
Compound 168
CCOC(=O)c1c(C(C)C)[nH]c2cc([N+](=O)[O-])c(F)cc12
ethyl5-fluoro-2-isopropyl-6-nitro-1H-indole-3-carboxylate
BrCc1ccccc1
benzyl bromide

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

The title compound was prepared from ethyl5-fluoro-2-isopropyl-6-nitro-1H-indole-3-carboxylate (Compound 168) and benzyl bromide by General Procedure J.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US08524917B2uspto-grants-2013_09