Reacción #6812

Ecuación de reacción

triphenylphosphine

N-(3-bromopropyl)phthalimide

→

3-phthalimidopropyltriphenylphosphonium bromide

Rendimiento 46.1%

Disolventes

toluene

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe 3-phthalimidopropyltriphenylphosphonium bromide was prepared
2. 2
   TemperaturaThe mixture was heated
3. 3
   Temperaturato reflux overnight
4. 4
   OtroThe white solid so formed
5. 5
   Otrowas isolated by filtration
6. 6
   Otrodried under vacuum

Procedimiento

The 3-phthalimidopropyltriphenylphosphonium bromide was prepared as follows. To a solution of triphenylphosphine (24.5 g, Aldrich, U.S.A.) in toluene (200 mL) was added N-(3-bromopropyl)phthalimide (25 g, Aldrich, U.S.A.). The mixture was heated to reflux overnight. The white solid so formed was isolated by filtration and dried under vacuum to yield 3-phthalimidopropyltriphenylphosphonium bromide (22.8 g).

Fuente