Reacción #679305

Ecuación de reacción

2-nitrobenzyl alcohol

isocyanatoethyl methacrylate

isocyanate

→

2-({[(2-nitrobenzyl)oxy]carbonyl}amino)ethyl 2-methylacrylate

Disolventes

toluene

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroA monomer was prepared
2. 2
   OtroThe jar was sealed
3. 3
   Otroplaced in a 70° C.
4. 4
   Otrofor 2 hours
5. 5
   OtroThe resulting reaction mixture
6. 6
   TemperaturaThe reaction mixture was cooled
7. 7
   OtroThe jar was then capped and refrigerated overnight
8. 8
   OtroThe next day, the white crystals that had separated
9. 9
   Filtraciónwere filtered off
10. 10
    Otrodried
11. 11
    Otroto produce 26.9 g of NBMA

Procedimiento

A monomer was prepared by adding 14.4 g 2-nitrobenzyl alcohol (Alfa Aesar, Ward Hill, Mass.), 14.6 g isocyanatoethyl methacrylate (Aldrich, Milwaukee, Wis.), and 1 drop of dibutyltin dilaurate (Alfa Aesar, Ward Hill, Mass.) to a 4-ounce jar. The jar was sealed and placed in a 70° C. oven for 2 hours. The resulting reaction mixture was analyzed by infrared spectroscopy (Nexus 670 FT-IR E.S.P.; Thermo Nicolet Corporation; Madison, Wis.) which showed no absorbance at 2250 cm−1, indicating substantially no remaining isocyanate functionality. The reaction mixture was cooled and 40 mL of toluene were added to it. The jar was then capped and refrigerated overnight. The next day, the white crystals that had separated were filtered off and dried to produce 26.9 g of NBMA. NMR and IR spectral analyses confirmed the structure of the product.

Fuente