Reacción #67814

Ecuación de reacción

3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid

intermediate 1

3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid

1-(3-amino-propyl)-pyrrolidin-2-one

→

3-[(2-fluoro-4-iodophenyl)amino]-N-[3-(2-oxopyrrolidin-1-yl)propyl]isonicotinamide

Condiciones de reacción

Procedimiento

3-[(2-fluoro-4-iodophenyl)amino]-N-[3-(2-oxopyrrolidin-1-yl)propyl]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.6 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.85 mmol of 1-(3-amino-propyl)-pyrrolidin-2-one LC/MS [8.70 min; 483 (M+1)].

Fuente