Reacción #67786

Ecuación de reacción

3-fluoroisonicotinic acid

hydrogen peroxide

→

3-fluoroisonicotinic acid 1-oxide

Disolventes

acetic acid

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe solvent was removed

Procedimiento

To a solution of 3-fluoroisonicotinic acid (5.0 g, 35.33 mmol) in acetic acid (25 ml) was added hydrogen peroxide (6 ml). The reaction mixture was stirred at 70-80° C. overnight. The solvent was removed to obtain 5.5 g of 3-fluoroisonicotinic acid 1-oxide in quantitative yield.

Fuente