Reacción #67740

ord-fae6739cd9de41b5a46023d89559263c

Ecuación de reacción

COc1ccccc1Nc1cccc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)n1
1-(benzo[d][1,3]dioxol-5-yl)-N-(6-(2-methoxyphenylamino)pyridin-2-yl)cyclopropanecarboxamide
CNc1ccccc1OC
2-methoxy-N-methylaniline
O=C(Nc1cccc(Br)n1)C1(c2ccc3c(c2)OCO3)CC1
1-(benzo[d][1,3]dioxol-5-yl)-N-(6-bromopyridin-2-yl)cyclopropanecarboxamide
→
COc1ccccc1N(C)c1cccc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)n1
1-(Benzo[d][1,3]dioxol-5-yl)-N-(6-((2-methoxyphenyl)(methyl)amino)pyridin-2-yl)cyclopropanecarboxamide

Reactantes

COc1ccccc1Nc1cccc(NC(=O)C2(c3ccc4c(c3)OCO4)CC2)n1
1-(benzo[d][1,3]dioxol-5-yl)-N-(6-(2-methoxyphenylamino)pyridin-2-yl)cyclopropanecarboxamide
CNc1ccccc1OC
2-methoxy-N-methylaniline
O=C(Nc1cccc(Br)n1)C1(c2ccc3c(c2)OCO3)CC1
1-(benzo[d][1,3]dioxol-5-yl)-N-(6-bromopyridin-2-yl)cyclopropanecarboxamide

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

1-(Benzo[d][1,3]dioxol-5-yl)-N-(6-((2-methoxyphenyl)(methyl)amino)pyridin-2-yl)cyclopropanecarboxamide was synthesized using the procedure of 1-(benzo[d][1,3]dioxol-5-yl)-N-(6-(2-methoxyphenylamino)pyridin-2-yl)cyclopropanecarboxamide by reacting 2-methoxy-N-methylaniline with 1-(benzo[d][1,3]dioxol-5-yl)-N-(6-bromopyridin-2-yl)cyclopropanecarboxamide.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US08524910B2uspto-grants-2013_09