Reacción #674357

ord-430e045d3ac94577b9bb243b2eaa24cc

Ecuación de reacción

NS(=O)(=O)Cc1cccc(Nc2ncnc(Cl)n2)c1
A1
NS(=O)(=O)Cc1cccc(Nc2ncnc(Cl)n2)c1
3-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide
c1cc2c(s1)CCNC2
4,5,6,7-tetrahydrothieno[3,2-c]pyridine
→
NS(=O)(=O)Cc1cccc(Nc2ncnc(N3CCc4sccc4C3)n2)c1
3-[(4-(6,7-Dihydrothieno[3,2-c]pyridin-5(4H)-yl)-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide

Reactantes

NS(=O)(=O)Cc1cccc(Nc2ncnc(Cl)n2)c1
A1
NS(=O)(=O)Cc1cccc(Nc2ncnc(Cl)n2)c1
3-[(4-Chloro-1,3,5-triazin-2-yl)amino]benzenemethanesulfonamide
c1cc2c(s1)CCNC2
4,5,6,7-tetrahydrothieno[3,2-c]pyridine

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    OtroB43 was prepared

Procedimiento

B43 was prepared following the general procedure reported for B10 using A1 and 4,5,6,7-tetrahydrothieno[3,2-c]pyridine; yield: 88.6 mg (22%), white amorphous solid. MS (ES) C17H18N6O2S2 requires: 402. found: 403 (M+H)+.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US09226929B2uspto-grants-2016_01