Reacción #670904

Ecuación de reacción

1-[1-(4-nitrophenyl)pyrrolidin-3-yl]-1H-imidazole

dibromopropane

→

yellow powder ( 4 )

Rendimiento 189.3%

3-[1-(4-nitrophenyl)pyrrolidin-3-yl]-1-(3-{1-[1-(4-nitrophenyl)pyrrolidin-3-yl]-1H-imidazol-3-ium-3-yl}propyl)-1H-imidazol-3-ium dibromide

Rendimiento 189.3%

Disolventes

pentanol DMF

Condiciones de reacción

Tratamiento posterior

1. 1
   FiltraciónThe precipitate was filtered off while hot and
2. 2
   Lavadowashed with pentanol
3. 3
   Otrodrying the precipitate

Procedimiento

3.5 g (0.0135 mol) of 1-[1-(4-nitrophenyl)pyrrolidin-3-yl]-1H-imidazole were heated to 100° C. in 12 ml of a pentanol/DMF mixture (50/50). 1 g (0.005 mol) of dibromopropane was added. The reaction medium was heated at 115° C. for 17 hours. The precipitate was filtered off while hot and washed with pentanol and then with ether. After draining by suction and drying the precipitate, 3.4 g of yellow powder (4) were obtained. 33% yield.

Fuente