Reacción #6698

Ecuación de reacción

7-chlorolepidine

CH3I

diethyl ether

→

7-chloro-1-methyllepidinium iodide

Disolventes

CH3CN

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturaat reflux for two hours
2. 2
   Otroto give a yellow powder

Procedimiento

A portion of the 7-chlorolepidine (80 mg) prepared as above was methylated by heating with CH3I (0.5 ml) in CH3CN (1 ml) at reflux for two hours. The mixture was treated with diethyl ether, followed by centrifugation, to give a yellow powder.

Fuente