Reacción #669144

ord-4cd9d2f8740145f98a89fec295a82ac8

Ecuación de reacción

CC(=O)Nc1ccc(C(C)=O)cc1[N+](=O)[O-]
N-(4-acetyl-2-nitrophenyl)acetamide
O=S(=O)(O)O
sulfuric acid
→
CC(=O)c1ccc(N)c([N+](=O)[O-])c1
4-Acetyl-2-nitroaniline

Reactantes

CC(=O)Nc1ccc(C(C)=O)cc1[N+](=O)[O-]
N-(4-acetyl-2-nitrophenyl)acetamide
O=S(=O)(O)O
sulfuric acid

Reactivos

Ninguno

Disolventes

O
water
O
water

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    FiltraciónThe product was filtered off
  2. 2
    Lavadowashed with water
  3. 3
    Otrodried

Procedimiento

N-(4-acetyl-2-nitrophenyl)acetamide (26.5 g, 11.94 mmol) was added to a mixture of water and concentrated sulfuric acid, 150 ml (1:2). After 15 minutes the mixture was poured into water. The product was filtered off, washed with water and dried.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US05922724uspto-grants-1999_07