Reacción #6681

Ecuación de reacción

Cs2CO3

benzyl bromide

BzBn

ethyl 4-hydroxybenzoate

→

Ethyl 4-benzyloxybenzoate

Rendimiento 100.0%

Disolventes

DMF

water

Condiciones de reacción

Tratamiento posterior

1. 1
   Otrothe product was collected by extraction
2. 2
   LavadoThe organic solution was washed with brine
3. 3
   Secadodried over MgSO4
4. 4
   OtroAfter evaporation of solvent
5. 5
   Otropure product was obtained in yield of 100%

Procedimiento

35 mmol of benzyl bromide (BzBn, 35 mmol of ethyl 4-hydroxybenzoate (10), 14 g of Cs2CO3 and 40 ml of DMF were combined and stirred at RT ove night. Then the reaction mixture was poured into water and the product was collected by extraction. The organic solution was washed with brine and dried over MgSO4. After evaporation of solvent, pure product was obtained in yield of 100%.

Fuente