Reacción #65645

Ecuación de reacción

cyclohexylamine

atropic acid

N-methylmorpholine

iso-butyl chloroformate

→

product

Rendimiento 28.9%

N-Cyclohexyl-2-phenylpropenamide

Rendimiento 28.9%

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe crude product was purified by recrystallisation from cyclohexane

Procedimiento

This compound was made from atropic acid (10.48 g, 70.8 mmol), N-methylmorpholine (7.8 ml, 70.9 mmol), iso-butyl chloroformate (9.2 ml, 70.9 mmol), and cyclohexylamine (8.1 ml, 70.7 mmol) using the procedure described in Example 3. The crude product was purified by recrystallisation from cyclohexane to give the product (4.69 g), as white crystals, m.p. 131°-133°. (Found: C, 78.7; H, 8.8; N, 5.95. C15H19NO requires C, 78.6; H, 8.35; N, 6.1%.)

Fuente