Reacción #65632

Ecuación de reacción

8-chloro-dibenz[b,f]-[1,4]oxazepine

phthalic anhydride

→

title compound

Rendimiento 70.3%

2-[(8-chlorodibenz[b,f][1,4]oxazepin-10(11H)-yl)carbonyl]benzoic acid

Rendimiento 70.3%

Disolventes

THF

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturawas heated
2. 2
   Temperaturato reflux for 4 days
3. 3
   ConcentraciónThe mixture was concentrated
4. 4
   Otrothe residue was triturated with ether
5. 5
   FiltraciónThe precipitated solid was filtered

Procedimiento

A stirred mixture of 8-chloro-dibenz[b,f]-[1,4]oxazepine (3.35 g) and phthalic anhydride (2.13 g) in THF (40 mL) was heated to reflux for 4 days. The mixture was concentrated and the residue was triturated with ether. The precipitated solid was filtered to give the title compound as a white solid (3.84 g).

Fuente