Reacción #6500

Ecuación de reacción

2-hydroxyethyl methacrylate

diethyl oxalate

ethanol

→

2-ethoxalyloxyethyl methacrylate

Rendimiento 76.5%

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroA 500 ml flask equipped with a decanter
2. 2
   workup.ADDITIONwere added
3. 3
   TemperaturaThe mixture was heated
4. 4
   OtroThe reaction mixture was evaporated
5. 5
   Otroto remove excess diethyl oxalate
6. 6
   workup.DISTILLATIONdistilled under vacuum

Procedimiento

A 500 ml flask equipped with a decanter, a thermometer, a stirrer and an inlet for nitrogen gas was charged with 65.1 g (0.5 mol) of 2-hydroxyethyl methacrylate and 365.4 g (2.5 mol) of diethyl oxalate, to which 2 g (10 mmol) of p-toluenesulfonic acid (catalyst) and 4 g of 2-t-butylhydroquinone (polymerization inhibitor) were added. The mixture was heated to keep about 130° C. for 3 hours in nitrogen atmosphere with distilling 22 ml (0.38 mol) of ethanol away. The reaction mixture was evaporated to remove excess diethyl oxalate and then distilled under vacuum to obtain 64.8 g (yield 76.5%) of 2-ethoxalyloxyethyl methacrylate (bp 84°-125° C./0.4 mmHg).

Fuente