Reacción #64356

Ecuación de reacción

N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide

ethyl iodide

hydride

tetrahydrofuran

Dichloromethane

→

N-ethyl-N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturawas heated
2. 2
   Temperaturaat reflux for 30 minutes
3. 3
   Otroany insoluble matter was removed by filtration
4. 4
   OtroThe filtrate was recrystallized from a mixture of diethyl ether and n-hexane

Procedimiento

A mixture of 0.53 g of N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide, 1.60 g of ethyl iodide, 0.09 g of sodlum hydride, and 10 ml of tetrahydrofuran was heated at reflux for 30 minutes. Dichloromethane was added to the reaction mixture, and any insoluble matter was removed by filtration. The filtrate was recrystallized from a mixture of diethyl ether and n-hexane to obtain 0.45 g of N-ethyl-N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide represented by formula shown below.

Fuente