Reacción #64300

Ecuación de reacción

3-amino-1,2,5-thiadiazole hydrochloride

ethyl 2-methyl-3,4,6,-trifluorobenzoylacetate

ethyl orthoformate

acetic anhydride

→

Ethyl 3-(1,2,5-thiadiazole-3-ylamino)-2-(2-methyl-3,4,6-trifluorobenzoyl)acrylate

Condiciones de reacción

Tratamiento posterior

1. 1
   Otro157 (colorless needles) was prepared in a similar manner to Example 17

Procedimiento

Compound No. 157 (colorless needles) was prepared in a similar manner to Example 17, proceeding from the corresponding compounds ethyl 2-methyl-3,4,6,-trifluorobenzoylacetate, ethyl orthoformate, acetic anhydride and 3-amino-1,2,5-thiadiazole hydrochloride.

Fuente