Reacción #637186

ord-6132dcac8cb24b1ebef4269ed4b9aea0

Ecuación de reacción

COc1ccc2ccsc2c1
6-Methoxybenzo[b]thiophene
O=Cc1cc(Br)ccc1Cl
5-bromo-2-chlorobenzaldehyde
COc1ccc2cc(Cc3cc(Br)ccc3Cl)sc2c1
5-Bromo-2-chloro-1-(6-methoxybenzo[b]thiophen-2-ylmethyl)-benzene

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Tratamiento posterior

  1. 1
    workup.ADDITIONwere treated in a manner similar to Reference Example 7
  2. 2
    Otroto give the target compound

Procedimiento

6-Methoxybenzo[b]thiophene (see WO 97/25033) and 5-bromo-2-chlorobenzaldehyde obtained in Reference Example 16-(1) were treated in a manner similar to Reference Example 7 to give the target compound.

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07943788B2uspto-grants-2011_05