Reacción #632108

Ecuación de reacción

5-bromothiophene-2-carboxylic acid

3-amino-N-cyclopropyl-4-methylbenzamide hydrochloride

→

5-Bromo-N-(5-(cyclopropylcarbamoyl)-2-methylphenyl)thiophene-2-carboxamide

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroCompound a was prepared
2. 2
   OtroHPLC Ret time=3.16 min

Procedimiento

Compound a was prepared by coupling 5-bromothiophene-2-carboxylic acid with 3-amino-N-cyclopropyl-4-methylbenzamide hydrochloride (prepared as described in WO04071440) using the method described in Example 2. HPLC Ret time=3.16 min. LCMS [M+H]+ 379.15.

Fuente