Reacción #63124

Ecuación de reacción

4-[(2-hexyl-4-tetradecylphenoxy)methyl]-2,2-dimethyl-1,3-dioxolane

hydrochloric acid

→

desired compound

Rendimiento 98.5%

3-(2-Hexyl-4-tetradecylphenoxy)-1,2-propanediol

Rendimiento 98.5%

Disolventes

tetrahydrofuran

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturawas heated
2. 2
   Temperaturaat reflux for 4 hours
3. 3
   Temperaturato cool
4. 4
   Otrothe tetrahydrofuran removed under reduced pressure
5. 5
   ExtracciónThe mixture was then extracted several times with ethyl acetate
6. 6
   Lavadowashed with aqueous sodium bicarbonate
7. 7
   Otrodried
8. 8
   Otrothe solvent evaporated

Procedimiento

A mixture of 13.6 g of 4-[(2-hexyl-4-tetradecylphenoxy)methyl]-2,2-dimethyl-1,3-dioxolane, 10 ml of 5% hydrochloric acid and 250 ml of tetrahydrofuran was heated at reflux for 4 hours, then allowed to cool and the tetrahydrofuran removed under reduced pressure. The mixture was then extracted several times with ethyl acetate. The organic extracts were combined, washed with aqueous sodium bicarbonate, dried and the solvent evaporated, giving 12.3 g of the desired compound.

Fuente