Reacción #6287

Ecuación de reacción

4-hydroxymethyl-2-methoxy-2-phenyl-1,3-dioxolane

triethylamine

acryloyl chloride

→

4-acryloyloxymethyl-2-methoxy-2-phenyl-1,3-dioxolane

Disolventes

methylene chloride

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroThe crude product was purified by column chromatography over basic alumina

Procedimiento

The procedure of Example A was repeated, employing 21 grams (100 mmol.) of 4-hydroxymethyl-2-methoxy-2-phenyl-1,3-dioxolane, 25.3 grams (250 mmol.) of triethylamine, 9.5 grams (105 mmol.) of acryloyl chloride and 150 ml. of methylene chloride. The crude product was purified by column chromatography over basic alumina, using 15% (by volume) ethyl acetate in hexane as an eluant, to yield the desired 4-acryloyloxymethyl-2-methoxy-2-phenyl-1,3-dioxolane.

Fuente