Reacción #6271

Ecuación de reacción

rhodanine

3,5-di-tert-butyl-4-hydroxybenzaldehyde

piperidine

→

desired compound

Rendimiento 69.7%

5-(3,5-di-tert-butyl-4-hydroxyphenyl)methylenerhodanine

Rendimiento 69.7%

Disolventes

ethanol

Condiciones de reacción

Tratamiento posterior

1. 1
   Temperaturathe mixture was heated
2. 2
   Temperaturaunder reflux for 5 hours
3. 3
   TemperaturaAfter cooling
4. 4
   Filtraciónthe precipitated crystals were filtered
5. 5
   Lavadowashed with cooled ethanol

Procedimiento

To a solution of 14.6 g (110 mmol) of rhodanine and 25.7 g (110 mmol) of 3,5-di-tert-butyl-4-hydroxybenzaldehyde in 150 ml of ethanol, 1.08 ml (11.0 mmol) of piperidine was added, and the mixture was heated under reflux for 5 hours. After cooling, the precipitated crystals were filtered and washed with cooled ethanol to give 26.71 g of the desired compound (69.7% yield, pale yellow crystals).

Fuente