Reacción #62175

ord-c1f7b80577c4444990715f2175634604

Ecuación de reacción

CON(C)C(=O)c1ccc(OCc2ccc3ccccc3n2)cc1
N-Methoxy-N-methyl4-(quinolin-2-ylmethoxy)-benzamide
O=C(O)c1ccc(OCc2ccccc2)cc1F
4-Benzyloxy-2-fluoro-benzoic acid
→
CON(C)C(=O)c1ccc(OCc2ccccc2)cc1F
title compound
CON(C)C(=O)c1ccc(OCc2ccccc2)cc1F
4-Benzyloxy-2-fluoro-N-methoxy-N-methyl-benzamide

Reactantes

CON(C)C(=O)c1ccc(OCc2ccc3ccccc3n2)cc1
N-Methoxy-N-methyl4-(quinolin-2-ylmethoxy)-benzamide
O=C(O)c1ccc(OCc2ccccc2)cc1F
4-Benzyloxy-2-fluoro-benzoic acid

Reactivos

Ninguno

Condiciones de reacción

Condiciones detalladas
See reaction.notes.procedure_details.

Procedimiento

Following the procedure for the preparation of N-Methoxy-N-methyl4-(quinolin-2-ylmethoxy)-benzamide but substituting 4-Benzyloxy-2-fluoro-benzoic acid provided the title compound. MS: (M+H m/z=290.2).

Fuente

DOI: 10.6084/m9.figshare.5104873.v1Patente: US07429665B2uspto-grants-2008_09