Reacción #619155

Ecuación de reacción

sodium triacetoxyborohydride

1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea

acetic acid

thiomorpholine

→

desired product

Rendimiento 9.2%

1,1-Dicyclohexyl-3-(5-thiomorpholin-4-ylmethyl-thiazol-2-yl)-urea

Rendimiento 9.2%

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroPrepared

Procedimiento

Prepared as described in general procedure (P) using 1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea (60 mg, 0.18 mmol), acetic acid (11 μL, 0.18 mmol), thiomorpholine (21 μL, 0.22 mmol) and sodium triacetoxyborohydride (38 mg, 0.20 mmol) to afford 7 mg (9%) of the desired product after purification.

Fuente