Reacción #619143

Ecuación de reacción

1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea

cyclopentylamine

sodium triacetoxyborohydride

→

desired product

Rendimiento 37.1%

1,1-Dicyclohexyl-3-(5-cyclopentylaminomethyl-thiazol-2-yl)-urea

Rendimiento 37.1%

Condiciones de reacción

Tratamiento posterior

1. 1
   OtroPrepared

Procedimiento

Prepared as described in general procedure (P) using 1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea (100 mg, 0.30 mmol), cyclopentylamine (45 μL, 0.45 mmol) and sodium triacetoxyborohydride (102 mg, 0.48 mmol) to afford 45 mg (37%) of the desired product after purification.

Fuente